All products featured on Allure are independently selected by our editors.

However, we may receive compensation from retailers and/or from purchases of products through links in this article.

People usually look to peptides specifically, though, for their ability to smooth over fine lines.

Cosmetic items overlapping on a peach background. Center white bottle and blue jar. Sides Blue and white containers.

Source images: Courtesy of brands; Collage: Laneen Wells forAllure

They’ve long been touted as a non-invasive, topical way to emulateinjectable-like results.

There are also many ways to get your hands on them, whether in serum or cream form.

Here, 13 of the very best peptide moisturizers, as suggested by dermatologists and our staffers.

SkinCeuticals P-Tiox Serum black serum bottle on light gray background

Ive always been told Im an expressive personsometimes I let my face speak for itself!

However, that means forehead lines and furrows are a big concern," says commerce editor Sarah Han.

Key ingredients:niacinamide, peptides, and shea butter |Fragrance-free?yes

Best Value:Fig.

BeautyStat Cosmetics Peptide Wrinkle Relaxing Moisturizer white jar with pink lid on light gray background

1 Ceramide Moisturizer

Fig 1 Skincare

Ceramide Moisturizer

Fig.

1

Why it’s worth it:When Fig.

It’s also refreshingly affordable compared to other peptide moisturizers and gentle enough to use day and night.

A silver tube of Filorga Time-Filler 5XP on a light gray background

There’s also hyaluronic acid and glycerin involved, which boosts its hydration power.

It melts into skin without any sticky residue, and feels like an indulgence after a long day.

A creamy, bouncy formula that helps enhance skin elasticity, rounded out by red algae for intense hydration.

Skinfix Barrier+ Triple Lipid-Peptide Cream turquoise jar on light gray background

Peptides are generally considered safe to use without major risks of skin irritation.

He thinks that people even younger can start adding peptides into their routine if they feel called to.

Can you layer peptide creams with other AHAs and retinol?

Youth to the People Polypeptide-121 Future Cream tub component on light gray background

How should a person shop for peptide moisturizers?

Are there any notable peptides to look out for?

However, there are a few with skin-smoothing benefits worth looking out for.

Shani Darden Hydration Peptide Cream component with black type on light gray background

Copper tripeptides similarly help with collagen production, Dr. Kim says, and boast anti-aging and anti-inflammatory benefits.

Still, he cautions people to be realistic with their expectations of these peptides.

“These things are not going to reduce wrinkles the way medical treatments will.”

Beautypie Youthbomb Biologic Collagen Peptide Cream orange jar with silver lid on light gray background

We review ingredients, scrutinize brand claims, and, when necessary, examine peer-reviewed scientific and medical studies.

To learn more information on our reporting and testing processes, read our completereviews process and methodology page.

Our staff and testers

A beauty product is a personal purchase.

Fig. 1 Ceramide Moisturizer cloudy bottle with pink layer under it and beige cap on light gray background

Hydrated skin is happy skin.

Medik8 Liquid Peptides Serum clear serum bottle with white dropper cap on light gray background

Isomers Matrixyl-4 Pur Collagen Peptide Serum brown serum bottle with pink label on light gray background

Paula’s Choice Resist Barrier Repair Advanced Moisturizer squat light blue bottle with white pump cap on light gray background

Estée Lauder Advanced Night Repair Overnight Treatment brown jar with gold lid on light gray background

Drunk Elephant Protini Polypeptide Cream white jar with turquoise lid on light grey background