I got Botox for the first time the year I turned 30.
Have I aged in the six years since?
Does itlooklike I have?
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Can you become less responsive to neuromodulators over time?
The answer to that question is not a simple yes or no.
There are many nuances that influence the effect that neuromodulators like Botox have on your muscles.
How do neuromodulators work?
Those are the lines that appear when you express emotions and are invisible when your face is at rest.
Neuromodulators inhibit the release of acetylcholine, a neurotransmitter that relays nerve signals to the muscle.
Over time, the nerve signals gradually resume their normal functionand the lines return.
Every person is different in their anatomy and how they animate, says Dr. Yang.
These are the factors that determine Botox dosing for each individual, not so much their age.
She takes note of any asymmetries and features like low-set brows.
What exactly is Botox resistance?
(ThoughDaxxify, the newest one on the block, may last as long as six months.)
(Botox wasFDA-approved as a treatment for migrainesin 2010.)
That said, in therapeutic cases much higher doses of botulinum toxin are used than in cosmetic patients.
In my practiceand Ive done hundreds of thousands of Botox injections[Botox resistance] is extremely rare.
What factors contribute to Botox resistance?
Keep in mind, as with any scientific phenomenon, correlation does not mean causation.
You should always wait at least three months between neuromodulator treatments.
Dr. Marchbein also points to the rise of medspas as a possible reason for an uptick in Botox resistance.
Inanother case, a patient under observation received Botox after getting the vaccine.
But one case is far (extremely far) from a study from which we can draw conclusions.
What can you do to prevent Botox resistance?
you might also consider trying a different brand than you used before.
Xeomin has the least amount of proteins and therefore the least opportunity for potential resistance, he says.
After your initial appointment and touch-up, you should not be back in your injectors chair before three months.
And if it’s possible for you to wait longer, thats even better.
Dr. Murphy agrees: For most people, I recommend getting Botox treatments every four months.
Typically, movement may return between two to three months.
Consider being the operative word.
If you want to give it a go, the recommended daily supplemental amount of zinc is 50 mg.
However, 50 mg. daily for a few days is unlikely to cause these symptoms, says Dr. Yang.
What happens if you stop responding to neuromodulators altogether?
On average, [it lasts] two-thirds of the time of Botox, says Dr. Idriss.
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